TRADENAME
Ibuprofen (IBUPROFEN)
On the preparation
Ibuprofen has anti-inflammatory, analgesic and antipyretic effect. The action of the active substance due to the suppression of prostaglandin synthesis by inhibiting cyclooxygenase - an enzyme involved in prostaglandin synthesis.
INDICATIONS AND DOSAGE
Ibuprofen is used for such diseases:
osteoarthritis;
rheumatoid arthritis;
gout;
ankylosing spondylitis;
myalgia;
neuralgia;
radiculitis;
bursitis;
soft tissue injuries and musculoskeletal system;
proctitis;
adnexitis;
diseases of upper respiratory tract;
toothache;
headache.
Acceptance of the drug depends on the type of the disease:
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ankylosing spondylitis and osteoarthritis - 3-4 times a day, 400-600 mg;
juvenile rheumatoid arthritis - a rate of 30-40 mg per 1 kg of body weight per day;
soft tissue injuries, sprains - 2-3 times a day, 600 mg;
moderate pain sensitivity syndrome - 3 times a day 400 mg.
The maximum daily dose is 2.4 g
OVERDOSE
In case of overdose possible manifestation of the following symptoms:
nausea;
vomiting;
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abdominal pain;
drowsiness;
lethargy;
noise in ears;
headache;
depression;
metabolic acidosis;
decrease in blood pressure;
bradycardia;
tachycardia;
respiratory arrest;
fibrilayatsiya atria;
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acute renal failure.
In case of overdose recommended gastric lavage within 1 hour after administration, forced diuresis, administration of activated charcoal and symptomatic therapy.